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ChatCOF

Advanced computational chemistry platform for Covalent Organic Framework (COF) analysis with immersive VR visualization. Predict, analyze, and optimize molecular building blocks with 3D recording and social sharing capabilities.

Comprehensive COF Analysis

Professional-grade molecular analysis tools for researchers and scientists

Molecular Analysis

Advanced geometric analysis, tripodal detection, and molecular descriptor calculation using RDKit and machine learning algorithms.

COF Prediction

Predict COF formation potential, topology, and stability. Analyze building block compatibility and framework dimensionality.

Synthesis Routes

Comprehensive retrosynthetic analysis with step-by-step synthesis protocols and optimal reaction conditions.

VR COF Nanobodies Exclusive

Immersive VR visualization with 756 atoms, 2,484 bonds, nanobody tethering sites, recording capabilities, and social sharing features. For registered users only.

Radiometal Complexes

Analyze radiometal complexation potential for diagnostic and therapeutic applications in nuclear medicine.

Green Chemistry

We integrate green chemistry heuristics into every prediction — making eco-friendly design the default.

VR COF Nanobodies Exclusive

Immerse yourself in 3D molecular visualization with advanced VR capabilities. Interactive nanobody tethering sites and real-time analysis. For registered users only.

Aptamer-COF VR Exclusive

Advanced binding analysis with aptamer functionalization. Nanobodies and aptamer COF functionalization materializes in seconds! For registered users only.

100+
Chemical Databases
8
Radiometal Types
15+
Analysis Modules
24/7
Available

How It Works

Simple four-step process for comprehensive molecular analysis

1
Input Your Molecule

Input SMILES or InChI strings for both single molecule and building block combinations.

2
AI-Powered Analysis

Our advanced algorithms analyze molecular properties, predict COF and MOP formation, and evaluate synthesis routes.

3
Explore in VR

Visualize results in immersive VR with 3D molecular structures, nanobody sites, and interactive controls.

4
Record & Share

Record VR sessions, share on social media, and export in multiple formats (CIF, PDB, JSON, WebM).

Advanced Capabilities

Professional-grade tools for cutting-edge materials research

Professional Chemical Naming

ChemDraw/ACD-quality molecule name resolution using PubChem, NIH Chemical Identifier Resolver, and OPSIN databases.

Machine Learning Predictions

AI-powered topology prediction, stability analysis, and synthetic feasibility assessment with high accuracy.

Multiple Synthesis Approaches

Solvothermal, room temperature, mechanochemical, and microwave synthesis protocols with detailed procedures.

VR Recording & Sharing Exclusive

Record immersive VR molecular visualizations and share directly to Twitter, LinkedIn, YouTube, and other platforms. For signed up users only.

Multiple Export Formats

Export results in JSON, CSV, CIF, PDB, and WebM formats for seamless integration with other computational tools.

Ready to Analyze Your Molecules?

Join researchers worldwide using ChatCOF for advanced COF analysis and materials discovery.