ChatCOF
Advanced computational chemistry platform for Covalent Organic Framework (COF) analysis. Predict, analyze, and optimize molecular building blocks for next-generation materials.
Comprehensive COF Analysis
Professional-grade molecular analysis tools for researchers and scientists
Molecular Analysis
Advanced geometric analysis, tripodal detection, and molecular descriptor calculation using RDKit and machine learning algorithms.
COF Prediction
Predict COF formation potential, topology, and stability. Analyze building block compatibility and framework dimensionality.
Synthesis Routes
Comprehensive retrosynthetic analysis with step-by-step synthesis protocols and optimal reaction conditions.
3D Visualization
Interactive 3D topology visualization with pore analysis and framework structure exploration using Three.js.
Radiometal Complexes
Analyze radiometal complexation potential for diagnostic and therapeutic applications in nuclear medicine.
Green Chemistry
We integrate green chemistry heuristics into every prediction — making eco-friendly design the default.
How It Works
Simple four-step process for comprehensive molecular analysis
Input Your Molecule
Input SMILES or InChI strings for both single molecule and building block combinations.
AI-Powered Analysis
Our advanced algorithms analyze molecular properties, predict COF and MOP formation, and evaluate synthesis routes.
Get Detailed Results
Receive comprehensive reports with 3D visualizations, synthesis protocols, and export options.
Export & Share
Download results in multiple formats (CIF, PDB, JSON) and share with your research team.
Advanced Capabilities
Professional-grade tools for cutting-edge materials research
Professional Chemical Naming
ChemDraw/ACD-quality molecule name resolution using PubChem, NIH Chemical Identifier Resolver, and OPSIN databases.
Machine Learning Predictions
AI-powered topology prediction, stability analysis, and synthetic feasibility assessment with high accuracy.
Multiple Synthesis Approaches
Solvothermal, room temperature, mechanochemical, and microwave synthesis protocols with detailed procedures.
Multiple Export Formats
Export results in JSON, CSV, CIF, and PDB formats for seamless integration with other computational tools.
Ready to Analyze Your Molecules?
Join researchers worldwide using ChatCOF for advanced COF analysis and materials discovery.